A decade after the heroic defeat of the monstrous Kraken, Perseus, the demigod son of Zeus, attempts to live a quieter life as a village fisherman and the sole father of his 10-year-old son, Helius. Meanwhile, a struggle for supremacy rages between the gods and the titans. Dangerously weakened by humanity’s lack of devotion, the gods are losing control of the imprisoned titans and their fierce leader, Cronus, father of the long-ruling brothers Zeus, Hades, and Poseidon.
The triumvirate had overthrown his powerful father long ago, leaving him to rot in the shadowy abyss of Tartarus, a dungeon found deep in the cavernous underworld. Perseus cannot ignore his true calling when Hades, along with Zeus’ divine son Ares (Edgar Ramirez), switch allegiances and make a deal with Cronus to capture Zeus. The Titans’ strength grows stronger as Zeus’s remaining divine powers are siphoned and hell breaks loose on earth. With the help of the warrior queen Andromeda (Rosamund Pike), Poseidon’s demigod son Argenor (Toby Kebbell) and the fallen god Hephaestus (Bill Nighy), Perseus bravely embarks on a treacherous quest into the underworld to rescue Zeus, overthrow the Titans and save humanity.